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Oxidative stress, aging, and diseases

Obesity is associated with macrophage accumulation in adipose tissue

However, these compounds are widely distributed in nature and often suffer from poor bioavailability, raising questions about the translational relevance of their observed effects in vitro

This ratio was then normalized to the fed control condition

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For the Cytochrome-C release assay, cells were seeded on coverslips in a 24-well plate and incubated for 5d total with the pan-caspase-inhibitor QVD-OPH (20 M in 500l)