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The nanoparticles of silibinin exhibited antioxidant effects against intracellular oxidative stress by upregulating the Nrf2/ARE pathway, reducing ROS, modulating antioxidant enzyme responsiveness, and inhibiting downstream pathways of mitochondrial damage (Ding et al., 2022)

309 Activated immune cells preferentially utilize lactate to enhance their functionality

Metformin Metformin, a diabetes medication, activates AMPK, improving energy balance and mimicking caloric restriction