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For example, the glutathione conjugate of hexachlorobutadiene is processed in the kidneys into reactive intermediates, leading to nephrotoxicity

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Concurrently, enhanced endogenous LC3B puncta formation was observed in PTX-treated cells with higher levels observed in PTX-resistant counterparts ( Figure 4D )

Similarly, preliminary results in our group indicate that ASCT2 is not involved in cysteine uptake in surviving xCT-ASCT2 double knockout PDAC cells in presence of -mercaptoethanol