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The inhibitory effects of SFN could be abolished by exogenously supplied GSH and by the GSH replenishing antioxidant N-acetylcysteine (NAC)

found that the dysregulation of zinc homeostasis in esophageal tumorigenesis is mainly reflected in the upregulation of ZIP5 and the downregulation of the zinc metabolism protein MT1G using cDNA microarray

The short duration of the intervention (eight weeks) may not capture the long-term effects or sustainability of the intermittent fasting regimen

For others, their system may need a more regular top-up to maintain optimal levels

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Intakes of vitamins a, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies