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The mechanistic core of the finding was that Dihexa activated the PI3K/AKT signaling pathway in the brains of the APP/PS1 mice, and that the PI3K inhibitor wortmannin reversed Dihexas anti-inflammatory and anti-apoptotic effects [5]

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Pyroptosis Pyroptosis, a type ofprogrammed cell death, relies on inflammasome activation, characterized by cellular swelling, membrane disruption, and the secretion of pro-inflammatory cytokines [230]

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In the liver, glutathione attaches to fat-soluble toxins and heavy metals, turning them into water-soluble compounds that the body can easily flush out