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Although the human body can produce glutathione on its own, production can have difficulty keeping up in times of excess stress, immune challenges, unhealthy microbial environments, or during aging, as glutathione status can decline with the natural aging process

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EMBO Rep 6: 2832 [DOI] [PMC free article] [PubMed] [Google Scholar] Frand AR, Kaiser CA (1998) The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum

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