The class also carries pancreatitis and gallbladder warnings
doi: 10.1186/s13045-019-0720-y
PMCID: PMC6627396 Morse RP, Rockenmacher S, Pyeritz RE, Sanders SP, Bieber FR, Lin A, MacLeod P, Hall B, Graham JM Jr
Mutations in FOXO genes have been suggested to cause hyperglycemia and hyperlipidemia and may even increase the risk of carcinogenesis in test models
People with Certain Medications Long-term use of certain medications, like proton pump inhibitors, H2 receptor antagonists, or metformin, can interfere with B12 absorption
Paul Talalay and researchers at Johns Hopkins University linked these findings (Prochaska et al., 1992) and identified sulforaphane, isolated from broccoli, as a potent inducer of phase II detoxification enzymes including glutathione-S-transferase (GST) and NAD(P)H oxidoreductase 1 (NQO1) (Zhang et al., 1992)