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Isolated perfusion with 1.0 g/kg of the cytotoxic xenobiotic 5-FU or hyperthermia of 41 degrees C 10 min resulted in 90% to 100% mortality in rats, with extensive, patchy necrosis, and infarction on histologic examination (Miyazaki et al

For fat to be used as an energy source it must be transported to the mitochondria

S., Pereira, K

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