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The peptide stimulates expression of early growth response 1 (EGR-1) gene, which regulates cytokine and growth factor generation along with early extracellular matrix formation, while simultaneously inducing its repressor NAB2 to prevent excessive angiogenic signaling

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The clone comprised approximately 213 kb and was mapped to ECA27q17

However, it should be noted that among the amino acids present in breast milk, circadian fluctuations are observed particularly in tryptophan, with levels rising at night, peaking in the early morning hours, and reaching their lowest levels in the afternoon [7, 23]

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