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Additionally, the selective nature of these cell death mechanisms, which rely on the disruption of iron and copper homeostasis, makes them more likely to affect cancer cells preferentially, thereby minimizing collateral damage to healthy tissues
In: Lawrence JM, Casagrande SS, Herman WH, Wexler DJ, Cefalu WT (eds) Diabetes in America [Internet]
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Inhibition of SHMT2 catalytic activity during embryonic development leads to insufficient dTTP supply and replication stress during the first mitosis, resulting in failure of pronuclear fusion and developmental arrest [37]
Glutamine supplementation contributes to the proper proliferation of intestinal mucosa cells and their integrity, resulting in decreased intestinal permeability and systemic infections
