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Less common reactions include contact dermatitis (a rash or itching that doesnt resolve), persistent redness, or a localized copper reaction

The peptide retains activity in human gastric juice for more than 24 hours, tolerates pH from 1 to 11, and resists multiple proteolytic enzymes, properties that derive from the high proline content (four of fifteen residues) and the absence of cleavage-prone motifs

Front Pharmacol 5:151 Stamler JS, Simon DI, Osborne JA, Mullins ME, Jaraki O, Michel T, Singel DJ, Loscalzo J (1992) S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds

Headache Nausea Vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet 5

Migraine sufferers have an elevated risk of developing vertigo, as do older people, women, and people with a family history of the condition