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However, the translational gap between the in vitro efficacy and the in vivo performance of many bioactive compounds (BACs) remains a major bottleneck in the development of efficacious nutraceutical products (1, 2)

Johnson, S., & Imai, S

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434,435,436,437 The majority of phase II and III trials center around neurotransmitter receptors and A mechanisms, while tau and inflammation drugs are more prominent in phase II, often featuring repurposed compounds

In some embodiments, each long-chain fatty acid independently comprises 13, 14, 15, 16, 17, 18, 19, 20, 21, or 22 carbon atoms in the carbon chain

The exact number depends on skin type, tone, and lifestyle factors such as sun exposure and diet