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Thus, given a large range of comparisons of different methods of drug administration in one model, along with the used animal models, the obtained results could be regarded as very reliable

This disruption suggests a possible role in experimental models of coagulation and inflammation, opening avenues for further investigation into its regulatory capacity

High-sugar, high-fat (HSHF) diets significantly lead to an imbalance in the ratio of bacteria in the phylum Acidobacteria, Firmicutes and Thick-walled bacteria to those in the phylum Anaplasma, Aspergillus, Cyanobacteria, and Actinobacteria, which impairs the gut barrier function, and activates microglial cells in the brain, generating inflammation and affecting the cholinergic system to increase the risk of cognitive dysfunction (58, 59)

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