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Further, with the discovery of glutathione (GSH) and several other molecules that contain Se (selenoproteins), a biochemical function was assigned to this element

Inhibition of fatty acid catabolism augments the efficacy of oxaliplatin-based chemotherapy in gastrointestinal cancers

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Shorthand notations for oxidized lipids are given using LipidLynxX system v0.9.24 42

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Accordingly, individual siRNA inhibition of stearoyl-CoA desaturase 1 ( Scd1 ), Fads2 , or very-long-chain 3-oxoacyl-CoA reductase ( Hsd17b12 ) did not protect against ferroptosis, while pooling all three siRNAs partially protected (Fig