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Ethics declarations Authors note These results were presented in parts at the Metabolomics in Life Science conference, 2728 January 2026, Ume, Sweden

2021 study found similarly that more aggressive parameters are not necessarily better shallower needle depths performed equally well as deeper ones

That enzyme is NNMT, nicotinamide N-methyltransferase

10.1038/nrn1683 Nat

Jssica Bassetto Carra, Maria Laura Goussain Darido, Camila Felix Vecchi, Mariana Carla de Oliveira, Ricardo Lus Nascimento de Matos, Pietra Mitiko Tateyama Pattini, Bianca Larissa Masquetti, Beatriz da Silva Tavares, Marcos Luciano Bruschi, Ana Paula Frederico Rodrigues Loureiro Bracarense, Ren Oliveira do Couto, Rubia Casagrande, Sandra Regina Georgetti, Waldiceu A

Lipid and Glucose Metabolism: Enhances insulin sensitivity and lipid metabolism, benefiting metabolic disorders