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However, following APAP toxicity, endogenous glucuronide and sulfate cofactors become depleted, leading to increased concentrations of NAPQI and rapid depletion of cellular GSH

The weight loss is driven by a ~25% increase in whole-body fat oxidation and resting energy expenditure

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(More information) There is no scientific evidence that large amounts of vitamin C (up to 10 grams [g]/day in adults) exert any adverse or toxic effects