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Blood tests include: Glomerular filtration rate (GFR), the most important measure of kidney function and one that declines with age Creatinine and blood urea nitrogen (BUN) Cystatin C, a more sensitive indicator of GFR than creatinine that Life Extension reported on nearly a decade ago Urine tests include: Urine output, osmolality, and specific gravity: designed to measure how much urine is made and how concentrated it is Urine protein, as the presence of elevated amounts in patients with diabetes, hypertension, or other diseases is a powerful predictor of chronic kidney disease progression Dietary and Lifestyle Considerations Avoid or minimize the use of NSAIDs by using the lowest effective dose for the shortest period of time Eat a Mediterranean-style diet or the DASH (Dietary Approaches to Stop Hypertension) diet that is low in animal protein and high-glycemic carbohydrates, and high in vegetables, fruits, unsaturated fats, and fiber Increase dietary potassium and decrease dietary sodium Make sure to get enough vitamin D, vitamin B6, and vitamin B12 Note: Patients with advanced kidney disease should consult with their physician before making any dietary changes

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By shaping these pathways, TB-500 appears to offer researchers a model for examining potential anti-inflammatory mechanisms and their regulation

The bioavailability of curcumin can be increased with the addition of fat and a component of black pepper called piperine