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Balestri, Martina, et al

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FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3

They want to do it right with purity, with processing, and making sure that anything they make, especially a sterile compound, which is going to be anything injected, eye drops, things you inject in yourself, whether it's IV, sub-Q, or intramuscular, they're considered sterile