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A product of lipid peroxidation, 4-hydroxynonenal, has been shown to induce apoptosis in neuroblastoma cells by elevating the levels of p53, p63 and p73 and p63 staining has been used as a marker for prostatic adenocarcinoma where lack of p63 staining indicates malignant prostatic adenocarcinoma [14,18]

One with the contralateral area and sham stroke area, another with saline and rt-PA 4h, and rt-PA 1h in between

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Outside the primary indication, it is also used in research and compounding contexts to reconstitute compatible sterile powders

Role of melatonin in Alzheimer's disease: from preclinical studies to novel melatonin-based therapies