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They have discovered that polyphenols may exhibit the ability to scavenge free radicals through (1) direct reaction with reactive oxygen species (ROS), (2) enhanced dismutation of free radicals to compounds with much lower reactivity, (3) inhibition of catalase enzyme activity, (4) increased activity of antioxidant enzymes such as SOD, (5) chelation with pro-oxidative metals like iron and copper, and (6) increasing the effectiveness of other small antioxidants like tocopherols and ascorbic acid [208, 209]
If they could have just addressed that one thing, in the context of also cleaning up other diet and lifestyle issues, that may have been the bigger global pillar that needed to be addressed rather than potential copper insufficiency, as you mentioned
Another proposed mechanism involves the regulation of inflammatory cascades
Production MD simulations were executed under isothermal-isobaric conditions (300 K, 1 bar) within 100 ns using the leapfrog algorithm
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