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doi: 10.1016/j.ejphar.2008.03.008

Our results show that glutathione efflux from hepatocytes results in high local concentrations of both glutathione and cysteine in liver sinusoids, which transforms the nanoparticle surface chemistry, reduces its affinity to serum protein and significantly alters its blood retention, targeting and clearance

Maes M, Maiter D, Thissen JP, Underwood LE, Ketelslegers JM

N.MohamedS

Systemic adverse effects are uncommon

Hypoxic Ischemic Encephalopathy (HIE) is one of the major brain disorder occur in infant when an infants brain doesnt receive enough oxygen and blood [27]