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Third, ferroptosis inducers, while targeting tumor cells, may inadvertently impact immune cells in the TME, potentially compromising the immune response and attenuating overall antitumor efficacy

Chen X, Guo C, Kong J

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It interacts with neurotransmitter pathways involving serotonin, norepinephrine, and GABA, contributing to its research value in neuroendocrine and circadian rhythm studies

Interference of the p53-FOXO4 interaction resulted in selective apoptosis of senescent cells and restoration of tissue homeostasis in multiple mouse models