Potential pathways of abnormal Tau and -Synuclein dissemination in sporadic Alzheimers and Parkinsons diseases
A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis
The diabetes gene Hhex maintains delta-cell differentiation and islet function
No interpretations extend beyond analytical research contexts, and no claims are made regarding biological outcomes, clinical relevance, or applicability outside controlled experimental systems
One of the distinctive features of IGF-1 LR3 is its reduced affinity for insulin-like growth factor binding proteins (IGFBPs), a family of proteins that regulate the distribution and accessibility of IGFs within circulation
As phase II enzymes, GSTs detoxify chemical compounds through catalyzing nucleophilic attack by the thiol group in reduced glutathione (GSH) on a wide range of electrophilic substrates [37, 40, 41]