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Silent information regulator 1 (Sirt1), an anti-inflammatory and anti-oxidative protein (316), increases the production of NO by activating endothelial NOS (eNOS) in endothelial cells in response to shear stress (317)

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The dimensions of each open-field chamber were 43 cm long 43 cm wide 30 cm high

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Brilhante et al., 2015)