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Following uptake into cells, fatty acids must be activated to acyl-CoA intermediates

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The interplay between hyperglycemia and oxidative stress contributes to the pathogenesis of diabetic complications, including neuropathy, nephropathy, retinopathy, and cardiovascular diseases [172]

On the other hand, in nonalcoholic steatohepatitis (NASH), the patient, in addition to fat, can present other alterations in the liver, such as inflammation and scars [50]

The construct design supports expression of the GSH1 ORF under control of the TEF1 promoter, while a counter-selectable marker is expressed under control of the GSH-regulated pGSH1

These defects render sperm unable to swim properly, causing male infertility [46]