Bizzaro N, Antico A
Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells
Nuciferine, an alkaloid derived from lotus leaves, is used clinically to manage hyperlipidemia and as an adjunct for weight control, owing to its lipid-regulating, insulin-secreting, vasodilatory, antihypertensive, antitumor, and immunomodulatory properties (90)
Marques M, Millas I, Jimenez A, Garcia-Colis E, Rodriguez-Feo JA, Velasco S, Barrientos A, Casado S, Lopez-Farre A
Scientific Background Small-molecule metabolic regulators are widely used in research exploring enzymatic signaling pathways
At that time, however, the view that babies metabolize drugs identically to adults was already known to be an unreliable and potentially dangerous assumption [9]