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Semax, a synthetic analog of ACTH(4-10), stimulates the expression of BDNF (Brain-Derived Neurotrophic Factor) and modulates serotonergic and dopaminergic systems

This results in membrane potential dissipation, ATP synthase inhibition, and energy depletion, culminating in fungal growth arrest and cell death (Nishikawa et al., 2010)

Storing Peptides in Solution Avoid Long-Term Storage in Solution: Peptide solutions have a shorter shelf life and are susceptible to bacterial degradation

Orphanet J Rare Dis 2012 Sep 18;7:68(6 pp)

Sometimes, other forms of hormone replacement therapy (HRT) may be necessary to achieve this balance