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When given by a trained professional, B12 injections are widely considered safe and well-tolerated

It can interfere with strength training, daily movement, and meal planning

It also requires the presence of a cyanide molecule and while the amount of cyanide is not dangerous, it does require the body to expend energy to convert and remove it

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10.1007/s13346-018-00613-y [DOI] [PubMed] 27.Bolaman Z, Kadikoylu G, Yukselen V (2003) Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study