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known cases of chronic disease under treatment such as tuberculosis, diabetes, hypertension, hypo or hyperthyroidism, pernicious anaemia, Crohns disease and current use of anticonvulsant drugs
When NNMT activity is reduced, less nicotinamide is methylated and wasted, allowing NAD pools to remain higher
Others can't take it because they're planning a pregnancy or have certain health conditions
The publications employed various concentrations and experimental conditions, tailored to the specific research model, experimental design and the aim of the analysis