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Poljsak B, uput D, Milisav I (2013) Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants, oxidative medicine and cellular longevity

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Nrf2 binds to antioxidant response elements (ARE) and oxidative stress-related proteins (including GSH, HO-1, and oxidoreductase I), and then scavenges cytotoxic electrophiles together with ROS (218)

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DSIP has further been shown to reduce corticotropin, and stimulate secretion of luteinizing hormone (LH)