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-Syn, a characteristic protein of Lewy bodies, is the earliest identified PD protein

10.1038/nmeth.4601 103 ReinkeA

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In addition, abnormal glial cells may also lead to changes in the extracellular environment, such as an increase in extracellular pH or disruption of ion balance, thereby affecting the normal function of DA neurons (Wang et al., 2003

To evaluate the functional significance of these spine changes Nlel-AnglV and Dihexa stimulated hippocampal neurons were immunostained against the glutamatergic presynaptic marker VGLUT1 (Balschun, Moechars et al

Rains AJH, Barson GJ, Crawford N et al (1960) A chemical and bacteriological study of gallstones