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It has demonstrated low skin irritability when applied topically, both with and without microneedle-assisted delivery

The difference between 1 unit and 2 units represents a 100% change in dose, from 200 mcg to 400 mcg

10.1111/iwj.13231 47 HallG.PhillipsT

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This overlap makes B12 deficiency easy to miss during GLP-1 therapy, because both the patient and the prescriber attribute these symptoms to the medication itself rather than investigating a correctable nutritional deficit