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Conversely, when crizotinib was combined with radiation therapy, inhibition of c-MET appeared to reduce radiosensitivity in vitro as measured by colony forming assay and in vivo using a mouse model [112]

As described above, GSTM2 modulated the size of LDs

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Mechanisms such as cellular senescence, genomic instability, telomere attrition, mitochondrial dysfunction, epigenetic alterations, and loss of proteostasis all contribute to an aging phenotype (Tenchov et al 2024) and are considered hallmarks or biomarkers for aging

1 In simple language: BPC-157 is a short, laboratory-produced peptide with a defined 15-residue sequence