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Stefanova N, Kaufmann WA, Humpel C, Poewe W, Wenning GK (2012) Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human -synuclein under oligodendrocyte promoter: implications for multiple system atrophy

As FAE has a relatively slow induction treatment therapy, combination therapy can also speed up the response

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( Reference Lawler, Barnes and Wu 34 ) demonstrated a direct doseresponse relationship of creatine concentration with superoxide anion (O 2 ), peroxynitrite (OONO ) and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) as determined by the rate of renewal of the ABTS + radical, and concluded that creatine has a significant role as an antioxidant

These results indicate that functionally defined SynCom can confer active anti-infective capacity through microbiotaimmune axis modulation