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Sragovich S, Merenlender-Wagner A, Gozes I

It is therefore possible that while CF carriers may not need the support of modifier genes for their personal survival in normal times, they may not easily tolerate further losses of CFTR expression following infection by SARS-CoV-2 virus

Common biomarkers used to identify senescent cells include the expression of p16 INK4a and p21 Cip1 , increased activity of SA--gal at pH 6.0, loss of the nuclear envelope protein Lamin B1, and the presence of persistent DNA damage foci [54]

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