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Much of the interest in IGF-1 signaling for muscle stems from a genuinely robust body of preclinical science on IGF-1s role in skeletal muscle growth and repair

Metabolite-based machine learning models reveal biomarkers of urinary, gait, and cognitive outcomes Following identification of metabolites associated with clinical response, we applied machine-learning approaches to model shunt outcomes using Partial Least SquaresDiscriminant Analysis (PLS-DA) and Support Vector Machine (SVM) classifiers

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The approval is backed by data from the Phase III SPOTLIGHT and GLOW studies, both of which met the primary endpoint of progression-free survival and key secondary endpoint of overall survival

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