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The high activity of 30 prompted a synthesis of the corresponding disulfide 32 with a 14-membered ring system anticipated be able to adopt a similar trans conformation as 30
The shorter sequence provides less structural stability, making refrigeration particularly important
Uses: COBANERVE-B12 Nasal Spray is indicated for the treatment of Vitamin B12 deficiency
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At this concentration, the standard 2 mg daily dose corresponds to the entire vial drawn whole, injected whole
In some embodiments, the otic formulation or composition comprises about 0.6% by weight of the poloxamer
