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YAP-independent mechanotransduction drives breast cancer progression

Lessons from look-back in acute liver failure

Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude

Moreover, pre-treatment with anti-MET antibodies blocked the beneficial effect exerted by HGF, while the one exerted by MSCs was blocked by anti-HGF antibody, showing that the positive effect was mostly dependent on the production of HGF

Cells were plated (2 10 7 cells per 150 mm plate) and grown for 24 h before transfection with Polyethylenimine (PEI, Sigma) according to the manufacturer's instructions

PMID 24091055