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[3] It is contraindicated in uncontrolled hypertension and is not recommended for people with significant cardiovascular disease

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Retrieved 2021-11-18

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Other researchers have shown that nursing home residents frequently have burdensome transitions at the end of life, including admission to an intensive care unit in the last month of life and late enrollment in hospice, 958 although the number of care transitions for nursing home residents with advanced cognitive impairment varies substantially across geographic regions of the United States

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