When we compared the synthesized compound 2 ( 2 syn ) to its counterpart formed through the photo-oxidation of compound 1 ( 2 irr ), we observed no differences in their optical properties and stereochemistry (Supplementary Figs
It occurs naturally in human plasma, saliva, and urine, and its plasma concentration declines significantly with age, from approximately 200 ng/mL in young adults to much lower levels in older individuals
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To increase energy expenditure, caffeine and other coffee compounds, such as diterpenes, can reduce the risk of obesity and loss of muscle mass