The impact of oxidative stress on spermatozoa ROS include a broad category of species including: a) Oxygen free radicals, such as superoxide anion (O 2 ), hydroxyl radical (OH) and hyperoxyl radical (HOO)
What would we want to address first before considering it
Split Dosing: If you are on a high-frequency protocol (more on this below), the morning will likely be one of your injection times
Inhibitors of specific signaling pathways were also incorporated: Compound C, an AMPK inhibitor, and MK-2206, an Akt1/2 inhibitor, both applied for 24 hours to determine the involvement of these pathways in the protective actions of Humanin [1]
This is actually the sweet spot for 10mg vials
The p38 MAPK pathway was also suppressed, leading to increased MCF-7 apoptosis