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Maintenance and discontinuation SURMOUNT-4, continue vs placebo switch after lead-in to about 20.9% loss: stopping regained about +14% over 52 weeks while continuing lost a further -5.5%

Therefore, novel therapeutic approaches aim to maintain the BBB integrity to slow the progression of neurological disorders

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Educate Yourself: Take time to understand how B12 works in the body and what it requires for optimal absorption and function

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Some case reports have documented the use of intravenous heparin (5000U twice daily) combined with intravenous insulin and achieved similar results (103)