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Usually, polyphenols in foods - except for the flavanols members - are in conjugated form (with carbohydrates), altering their solubility, digestion, and absorption properties, favoring their degradation and greatly limiting their absorption [52]

However, these clinical trials were conducted in Croatia and published in the early 2000s

LIGHT TINGLING & FAST-ABSORBING TEXTURE A gentle tingling sensation may occur upon application due to the delivery method

A similar scenario has in fact been reported recently in an alcoholic liver disease model in which long-term alcohol consumption activated NF-B in Kupffer cells, whereas NF-B activation in hepatocytes was inhibited 45

doi: 10.1038/s41586-021-03539-7 29 KolaczkowskaEKubesP

Grip strength and VO2 max emerge as top health biomarkers