Programs may start from a customer-supplied small molecule, an expected metabolite structure, or a labeled-handle concept, and can be aligned with broader amino acid conjugation, custom bioconjugation services, or thiol-reactive route planning informed by maleimide conjugation considerations when appropriate
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The single-pill formulation of AXS-05 (recommended dosage, twice daily) is likely to be advantageous for adherence, as single-pill regimens have demonstrated substantially better adherence and persistence in other chronic diseases than multi-treatment regimens [138,139,140]
10.1002/gps.1469 Int