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Angelidis AS, Smith GM (2003)

doi: 10.1167/iovs.11-9038 150

Phenylbutyrate is an HDAC inhibitor (similar action to butyrate from microbes) and TUDCA is a bile acid that can modulate gut microbiota composition as well as reduce ER stress in neurons [225]

Bera A, Srivastava A, Dubey V, Dixit AB, Tripathi M, Sharma M, et al

G_s-protein-coupled pathways are activated when CJC-1295 (No DAC) binds to pituitary GHRH receptors

The powerful effect of reduced GH activity on lifespan extension in mice has generated the hypothesis that pharmaceutically inhibiting, rather than increasing, GH action might delay ageing