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184 In gastric cancer, serum factors IL-6 and IL-8 can stimulate CD45 + CD33 low CD11b dim MDSCs to express ARG1 and ultimately inhibit CD8 + T cell function through the PI3K-AKT signaling pathway (Fig

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Dis (2008) 10:9314

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Understanding these mechanisms is essential for interpreting the breadth of effects reported across preclinical studies

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After full-text articles assessed for eligibility, three additional studies were excluded ( Table 1 )

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