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Chronic treatment with ascorbic acid inhibits the morphine withdrawal response in guinea-pigs

3.3 Ligand-based pharmacophore modeling Pharmacophore models were generated using the Phase module of Schrodinger 2023.1 from the molecules derived from the 9 ensemble dockings

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Spencer 2005

The mathematical model is deliberately kept minimal, for two reasons: to retain the essential antioxidant action of glutathione in the simplest, robust fashion, and to avoid over-fitting data

It is not approved for therapeutic use and remains for investigational and laboratory applications