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However, hydroxytyrosol (10 and 25 M) treatment prevented LPS-induced mastitis by increasing the levels of Nrf2, HO-1, NQO-1, TXNRD1, TNF-, IL-1, and IL-6 in mammary gland tissue (73)

Exposing cerebral mitochondria to THC was reported to induce a ten-fold increase in free radical leak and increased H 2 O 2 production [40], while in epithelial cells, THC upregulated inflammation-related genes and downregulated antioxidant-related genes [34]

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