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Vitamin B12 is an essential nutrient, and those that have that are deficient in this vitamin would need vitamin B12 injections every couple of months

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Figure 4 3.6 Lipoic acid modulates antioxidant enzyme activities under normal and Pb stress conditions To further investigate the effect of ALA in mitigating the detrimental effects of Pb stress and regulating antioxidant defense systems in tomato seedlings, we examined the activities of antioxidant enzymes, including SOD, POD, CAT, APX, GR and DHAR ( Figures 5AF )