There is no reliable data on the effects of prolonged use beyond a few weeks
It has become a significant public health concern, with a global prevalence rate of 4.4% (Monroe and Harkness, 2022
New attachment formation in the human periodontium by guided tissue regeneration Case reports
Do not let total calories drop below your daily floor (1,200 for women, 1,500 for men)
Numerous studies suggest that high-dose (often injected) carnitine supplements may improve some or all of these symptoms in patients undergoing a long-term hemodialysis treatment, but the studies have mostly been performed on a small number of patients and have not been double-blind studies
Some practitioners find that subcutaneous injection in the abdomen produces fewer GI side effects than thigh injections, though this is anecdotal rather than evidence-based